Split Butterfly Valve

AVM FLUID SBV Split Butterfly Valve – High-Containment Powder Transfer Made Smarter

At AVM (AOMI) FLUID, we specialize in high-containment transfer systems for potent active pharmaceutical ingredients (HPAPI) and toxic media. Our advanced SBV Split Butterfly Valve system is engineered to ensure the safest and most efficient powder handling in critical applications across the pharmaceutical, biotech, and chemical industries.

Unlike traditional valve systems, the AVM SBV offers superior docking flexibility with a floating active flange that allows for a generous misalignment tolerance of up to ±14 mm. This feature significantly enhances operational efficiency and minimizes production downtime.
The SBV system ensures complete containment by synchronously opening the active and passive halves of the valve, eliminating the risk of product contamination or operator exposure. With verified containment performance levels reaching <1μg/m³ (OEB5), our SBV valve supports full compliance with GMP, FDA, and cGMP regulations.
Additional advantages include:
Robust, compact design for repeated use in demanding environments
Tool-free assembly and disassembly for easy cleaning and maintenance
Compatibility with CIP/SIP systems, ensuring hygienic processing
Ideal for integration into isolators, RTP systems, and aseptic transfer lines
Choose AVM FLUID’s SBV Split Butterfly Valve for cutting-edge containment technology, intuitive operation, and maximum product and operator protection—all tailored to the highest global standards.

Parameter

•Ensure full compliance with industry regulatory standards.
•Enable safe handling of high-potency active pharmaceutical ingredients (HPAPI), protecting personnel and minimizing environmental contamination.
•Significantly reduce the risk of cross-contamination.
•Meet GMP compliance and strict product quality requirements.
•Maximize transfer efficiency for poorly flowing or high-value materials.
•Eliminate the need for costly, bulky secondary containment systems and high-class cleanroom environments.

Sealing Performance

The valve's containment performance is independently verified by the customer and third-party organizations in accordance with the ISPE SMEPAC (Standardized Measurement of Equipment Particulate Airborne Contamination) guideline.

Operation Sequence

Reduced to as low as 1 µg/m³ (OEB4 level)

High containment performance without the need for additional seals, vacuum, or extraction systems. Entry-level design offers a simple and cost-effective upgrade path to help meet essential GMP and containment requirements in manufacturing processes. Minimal component design ensures easy operation, cleaning, and maintenance, while delivering top-tier performance for an entry-level solution.

Reduced to as low as 0.7 µg/m³ (OEB5 level)

The use of soft sealing allows for a tighter fit between the valve discs, effectively preventing leakage issues caused by deformation due to metal fatigue after prolonged use.

Reduced to as low as 0.1 µg/m³ (OEB5 level)

Achieve rapid cleanliness performance through simple and quick extraction.
By using a recovery process integrated with the valve, it effectively prevents air contamination after valve separation.

﹤0.1 µg/m³ (OEB5 level)

This compact and efficient split-type valve delivers advanced performance at the nanogram level.
It features a sequence that enables simultaneous cleaning and extraction.
During the separation process, a sealed cavity is formed between the active and passive interfaces, allowing cleaning and extraction to occur concurrently. This effectively eliminates airborne particles that could cause contamination after the valve is fully disassembled.

Characteristics and advantages

Compliance and Quality Assurance

◆ Compliant with GMP standards
◆ Materials meet FDA requirements
◆ Conforms to European ATEX directive for hazardous areas
◆ Compliant with European Pressure Equipment Directive (PED)
◆ Meets European Machinery Directive
◆ Manufactured under ISO 9001 certified facilities
◆ Full material certification and batch traceability
◆ Independently validated according to sealing performance measurement guidelines (ISPE SMEPAC)

Cleaning and Sanitization

◆ Convenient and effective GMP-compliant cleaning design
◆ Suitable for cleaning inside high-pressure sterilization vessels
◆ In-place cleaning of exposed surfaces of the main valve
◆ Cleaning of passive valves and connected vessels

Using our specially designed Online Cleaning (WIP) system, efficient cleaning and sanitization of product contact surfaces and sealing areas are ensured.

Handling and Automation

The system ensures safe operation in hazardous or inaccessible areas, or where production scale prohibits manual handling:
◆ Fully automated or semi-automated versions available to meet application requirements;
◆ Status information and program interlock functions guaranteed through pneumatic or electric proximity sensors;
◆ Fully integrated and factory-tested control system;
◆ Repeatable and safe alignment with devices connected to hoists and docking systems;
◆ Lightweight versions available;
◆ GMP-compliant covers to protect valves when not in use.